HRID1457967

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7397

p-Toluenesulfonyl chloride

C7H7ClO2S

HCID330448

1-(Diphenylmethyl)azetidin-3-ol

C16H17NO

PRODUCTS

生成物

结构：Cc1ccc(S(=O)(=O)OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1

HCID15512651

3-Azetidinol, 1-(diphenylmethyl)-, 3-(4-methylbenzenesulfonate)

C23H23NO3S

PROCEDURE

实验过程

1-Benzhydryl-3-hydroxyazetidine is allowed to react with p-toluenesulfonyl chloride using an acid-removing agent to give 1-benzhydryl-3-(p-toluenesulfonyloxy)azetidine. This compound is allowed to react with diethyl malonate in the presence of a base to give diethyl (1-benzhydryl-3-azetidinyl)malonate.