反应详情

A mixture of dimethyl 4-(1,1-bis-ethoxycarbonylethyl)-3,5,6-trifluorophthalate (12.9 g, 30.7 mmol), hydrochloric acid (120 ml), and acetic acid (120 ml, was refluxed for 24 h. The reaction mixture was concentrated to dryness to give 9.0 g of the title compound as colorless crystals.

1. temperaturewas refluxed for 24 h
2. concentrationThe reaction mixture was concentrated to dryness