Hydrochloric Acid → HCID 22100516, compound

HRID 1458015Notes

Reaction equation

HRID 1458015 reaction equation
C([O:3][C:4]([C:6]([C:13]1[C:14]([F:29])=[C:15]([C:25]([O:27]C)=[O:26])[C:16](=[C:21]([F:24])[C:22]=1[F:23])[C:17]([O:19]C)=[O:18])(C(OCC)=O)[CH3:7])=[O:5])C.Cl>C(O)(=O)C>[C:4]([CH:6]([C:13]1[C:14]([F:29])=[C:15]([C:25]([OH:27])=[O:26])[C:16](=[C:21]([F:24])[C:22]=1[F:23])[C:17]([OH:19])=[O:18])[CH3:7])([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22100512HCID 22100512, compound

Product 1

HCID 22100516HCID 22100516, compoundYield 100.3%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of dimethyl 4-(1,1-bis-ethoxycarbonylethyl)-3,5,6-trifluorophthalate (12.9 g, 30.7 mmol), hydrochloric acid (120 ml), and acetic acid (120 ml, was refluxed for 24 h. The reaction mixture was concentrated to dryness to give 9.0 g of the title compound as colorless crystals.

Workup

  1. temperaturewas refluxed for 24 h
  2. concentrationThe reaction mixture was concentrated to dryness

Sources & evidence

ORD record
ord-400ebc8b6e6643ecb1669f8b8bbbcb70
Source dataset
uspto-grants-1998_12
Patent number
US05849757

Reaction notes

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