Water → HCID 22101712, compound

HRID 1458193Notes

Reaction equation

HRID 1458193 reaction equation
[CH2:1]([NH2:4])[CH2:2][CH3:3].[N:5]([C:13]([CH3:18])([CH3:17])[C:14]([O-:16])=O)=[N:6][C:7]([CH3:12])([CH3:11])[C:8]([O-:10])=O.C[O-].[Na+].O>CO>[N:6]([C:7]([CH3:11])([CH3:12])[C:8]([NH:4][CH2:1][CH2:2][CH3:3])=[O:10])=[N:5][C:13]([CH3:18])([CH3:17])[C:14]([NH:4][CH2:1][CH2:2][CH3:3])=[O:16]

Participants

6

Reactant 4

HCID 962WaterHCID 7852PropylamineHCID 10942334Sodium MethoxideHCID 22022530HCID 22022530, compound

Product 1

HCID 22101712HCID 22101712, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Conditions

Temperature
5 °C

Procedure

28.3 Grams of propylamine is mixed with 50 g of 2,2'-azobis (2-methyl propionate), and 10 g of 28% sodium methoxide solution in methanol and 10 ml of methanol are added thereto with stirring, followed by conducting a reaction at room temperature with stirring for 6 hours and keeping standing overnight. 100 Milliliter of water is added to the reaction solution and cooled to 5° C. to precipitate crystals. The crystals are recovered by filtration and dried to give 54.0 g (yield: 87%) of 2,2'-azobis(N-propyl-2-methyl propionamide) as pale yellow crystal. The solubility is shown in Table 1.

Workup

  1. additionare added
  2. customa reaction at room temperature
  3. stirringwith stirring for 6 hours
  4. customto precipitate crystals
  5. filtrationThe crystals are recovered by filtration
  6. customdried

Sources & evidence

ORD record
ord-124a1f2441414e49bf8e6b062cf268b1
Source dataset
uspto-grants-1998_12
Patent number
US05849888

Reaction notes

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