反应详情

A mixture of 1,2-diamino-4-chloro-5-trifluoromethylbenzene (13.4 g, 63.6 mmol) and diethyl oxalate (100 ml) was heated at reflux under nitrogen with stirring for 5 h. After being cooled, the solid which formed was filtered off and washed well with ether to afford a pale orange solid (14.5 g, 86%).

1. temperaturewas heated
2. temperatureat reflux under nitrogen
3. temperatureAfter being cooled
4. customthe solid which formed
5. filtrationwas filtered off
6. washwashed well with ether