Dabco → HCID 12431709, compound

HRID 1459035Notes

Reaction equation

HRID 1459035 reaction equation
Cl[C:2]([O:4][CH2:5][CH:6]([CH3:8])[CH3:7])=[O:3].[N:9]12CCN(CC1)C[CH2:10]2>>[C:10]([C:2]([O:4][CH2:5][CH:6]([CH3:8])[CH3:7])=[O:3])#[N:9]

Participants

3

Reactant 2

HCID 9237DabcoHCID 62365Isobutyl chloroformate

Product 1

HCID 12431709HCID 12431709, compoundYield 53,746%

Procedure

Isobutyl chloroformate (68.3 g; 0.5 mol), trimethylsilyl nitrile (49.5 g; 0.5 mol) and 1,4-diazabicyclo[2.2.2]octane (0.10 g; 0.9 mmol) was reacted to produce 61.5 g of isobutyl cyanoformate as a clear, colorless liquid (bp 52°-53° C./20 mmHg) Yield: 97% (theoretical); 98% purity 1H-NMR: δ4.1,d(2H), J=7 Hz; δ2.1, m(1H), δ1.00,d(6 H), J=7 Hz; IR 2250 cm-1 (CN), 1750 cm-1 (CO).

Sources & evidence

ORD record
ord-fcd553beba12484dabb82e93b42b9a95
Source dataset
uspto-grants-1998_12
Patent number
US05852207

Reaction notes

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