反应详情

Isobutyl chloroformate (68.3 g; 0.5 mol), trimethylsilyl nitrile (49.5 g; 0.5 mol) and 1,4-diazabicyclo[2.2.2]octane (0.10 g; 0.9 mmol) was reacted to produce 61.5 g of isobutyl cyanoformate as a clear, colorless liquid (bp 52°-53° C./20 mmHg) Yield: 97% (theoretical); 98% purity 1H-NMR: δ4.1,d(2H), J=7 Hz; δ2.1, m(1H), δ1.00,d(6 H), J=7 Hz; IR 2250 cm-1 (CN), 1750 cm-1 (CO).