HRID1460061
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with N-(2-(benzyloxy)ethyl)benzylamine, followed by reaction with 2ethyl-4-methylimidazole, reduction with fin (II) chloride, cyclization with carbonyldiimidazole, and hydrogenation with palladium on carbon in methanol containing 1.1 eq. NaOH at 50 psi and 50° C. for 24 h.
WORKUP
后处理
- customat 50 psi and 50° C.
- customfor 24 h.