Pyridine → HCID 15067105, compound

HRID 1460373Notes

Reaction equation

HRID 1460373 reaction equation
[CH2:1]([O:3][CH2:4][CH2:5][OH:6])[CH3:2].N1C=CC=CC=1.[S:13](Cl)([CH3:16])(=[O:15])=[O:14]>O1CCCC1>[CH3:16][S:13]([O:6][CH2:5][CH2:4][O:3][CH2:1][CH3:2])(=[O:15])=[O:14]

Participants

5

Reactant 3

HCID 1049PyridineHCID 8076Glycol monoethyl etherHCID 31297Methanesulfonyl chloride

Product 1

HCID 15067105HCID 15067105, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To 30g of 2-ethoxyethanol in 300ml of tetrahydrofuran 27.4ml of pyridine were added and 26.4ml of mesyl chloride added dropwise at room temperature over 15 minutes. The mixture was refluxed overnight, the solid that formed filtered off and the solvent evaporated off from the residue. The residue was distilled under 20m Hg to give 2-ethoxyethyl methanesulphonate.

Workup

  1. temperatureThe mixture was refluxed overnight
  2. customthe solid that formed
  3. filtrationfiltered off
  4. customthe solvent evaporated off from the residue
  5. distillationThe residue was distilled under 20m Hg

Sources & evidence

ORD record
ord-f8da1dc8ee6d42478c217b4800fba461
Source dataset
uspto-grants-1991_12
Patent number
US05071468

Reaction notes

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