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HRID1460617

反应详情

EQUATION

反应方程式

HRID 1460617 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CC1(C)Oc2ccc(C#N)cc2[C@@H](OC2=CC(=O)CC2)[C@@H]1O
HCID129348

3-Hydroxy-2,2-dimethyl-4-[(3-oxocyclopent-1-en-1-yl)oxy]-3,4-dihydro-2H-1-benzopyran-6-carbonitrile

C17H17NO4

结构：CNC1=CC(=O)CC1
HCID13217907

3-(Methylamino)cyclopent-2-en-1-one

C6H9NO

PRODUCTS

生成物

1
结构：CN(C1=CC(=O)CC1)[C@@H]1c2cc(C#N)ccc2OC(C)(C)[C@H]1O
HCID14301310

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

4.02 g of the epoxide of example 1 are reacted analogously to example 5 with 2.44 g N-methyl-3-amino-cyclopent-2-en-1-on and 660 mg of sodium hydride (80%) in dimethylsulfoxide. Usual working up yields crystalls of the title compound having a m.p. of 271°-74° C.