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HRID1460618

反应详情

EQUATION

反应方程式

HRID 1460618 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CC1(C)Oc2ccc(C#N)cc2[C@@H](OC2=CC(=O)CC2)[C@@H]1O
HCID129348

3-Hydroxy-2,2-dimethyl-4-[(3-oxocyclopent-1-en-1-yl)oxy]-3,4-dihydro-2H-1-benzopyran-6-carbonitrile

C17H17NO4

结构：CNC1=CC(=O)N(C)C1
HCID14301350

未命名化合物

PRODUCTS

生成物

1
结构：CN1CC(N(C)[C@@H]2c3cc(C#N)ccc3OC(C)(C)[C@H]2O)=CC1=O
HCID14301314

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

402 mg of the epoxide of example 1 in 4 ml of dimethylsulfoxide are reacted analogously to example 5 with 60 mg of sodium hydride and 25.2 mg of the amide obtained above. Usual work up yields the title compound having a m.p. of 266°-69° C.

WORKUP

后处理

  1. customobtained above