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HRID1460661

反应详情

EQUATION

反应方程式

HRID 1460661 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CCOC(=O)C1CCCNC1.Cl
HCID12896004

Ethyl piperidine-3-carboxylate--hydrogen chloride (1/1)

C8H16ClNO2

结构：Cc1ccccc1C(=COCCBr)c1ccc(F)cc1C
HCID54296314

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)[C@@H]1CCCN(CCOC=C(c2ccccc2C)c2ccc(F)cc2C)C1
HCID54574747

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

1-[2-(2-Bromethoxy)-1-(2-methylphenyl)ethenyl]-4-fluoro-2-methylbenzene (1.15 g, 0.0033 mol), the (R)-enantiomer of ethyl nipecotate hydrochloride (see example 1) (1.92 g, 0.0099 mol) and dried potassium carbonate (2.28 g, 0.0165 mol) were stirred in acetone (100 ml) at reflux temperature for 54 h.

WORKUP

后处理

  1. temperatureat reflux temperature for 54 h.