Ammonium Acetate → 5,6,7,8-Tetrahydroquinolin-7-amine

HRID 1461291Notes

Reaction equation

HRID 1461291 reaction equation
C([O-])(=O)C.[NH4+:5].[N:6]1[C:15]2[CH:14]=[CH:13][CH2:12][CH2:11][C:10]=2[CH:9]=[CH:8][CH:7]=1>C(OCC)(=O)C>[NH2:5][CH:13]1[CH2:14][C:15]2[N:6]=[CH:7][CH:8]=[CH:9][C:10]=2[CH2:11][CH2:12]1

Participants

4

Reactant 2

HCID 517165Ammonium AcetateHCID 123183175,6-Dihydroquinoline

Product 1

HCID 148359725,6,7,8-Tetrahydroquinolin-7-amine

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

This compound was prepared from ammonium acetate (1 54 g, 20 mmol) and 5,6-dihydroquinoline (2.31 g, 10 mmol) using the method described in Example 36 and ethyl acetate instead of ether as the extracting solvent.

Sources & evidence

ORD record
ord-bdf9e9eabb9b4bea854547bbdd2e0ff7
Source dataset
uspto-grants-1991_12
Patent number
US05075303

Reaction notes

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