Dimethylformamide → HCID 178521103, compound

HRID 1461565Notes

Reaction equation

HRID 1461565 reaction equation
[C-:1]1([C:6]([OH:8])=O)[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-:9]1[CH:13]=[CH:12][CH:11]=[CH:10]1.[Fe+2:14].CN(C=O)C.C(Cl)(=O)C([Cl:23])=O>C1(C)C=CC=CC=1>[C-:1]1([C:6]([Cl:23])=[O:8])[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-:9]1[CH:13]=[CH:12][CH:11]=[CH:10]1.[Fe+2:14]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 157642301271-42-7

Product 1

HCID 178521103HCID 178521103, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Ferrocene carboxylic acid (5.0 g, 21.7 mmol) was suspended in 40 mL of toluene containing a catalytic amount of DMF; oxalyl chloride (3.08 g, 24 mmol) was added dropwise (approx. addition time 30 min.). The resulting mixture was stirred at room temperature for 3 hours, filtered and the resulting solution used as such in Examples 3,4 and 5.

Workup

  1. addition(approx. addition time 30 min.)
  2. filtrationfiltered

Sources & evidence

ORD record
ord-afd3e20770014513a1f81d40f96301b9
Source dataset
uspto-grants-1991_12
Patent number
US05075471

Reaction notes

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