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HRID1461791

反应详情

EQUATION

反应方程式

HRID 1461791 的结构方程式

REACTANTS

反应物

4
结构：N#Cc1ccc(Br)cc1
HCID12162

Benzonitrile, 4-bromo-

C7H4BrN

结构：O=C1CCCCC12OCCO2
HCID12348074

1,4-Dioxaspiro[4.5]decan-6-one

C8H12O3

结构：C1CCOC1.CCCCCC
HCID21883165

未命名化合物

结构：[Li]CCCC
HCID178418339

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1ccc(C2(O)CCC3(CC2)OCCO3)cc1
HCID15023905

4-(8-Hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)benzonitrile

C15H17NO3

收率 70%

PROCEDURE

实验过程

4-Bromobenzonitrile was treated in THF-hexane with n-butyllithium at -100° C. Cyclohexanedione monoethylene ketal was added at -100° to give 70% yield of 11.