HRID1462267

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11430

Potassium Carbonate

CK2O3

HCID15809

4-Nitrothiophenol

C6H5NO2S

HCID74077

1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrachloro-

C8HCl4NO2

PRODUCTS

生成物

结构：O=C1NC(=O)c2c(Sc3ccc([N+](=O)[O-])cc3)c(Sc3ccc([N+](=O)[O-])cc3)c(Sc3ccc([N+](=O)[O-])cc3)c(Sc3ccc([N+](=O)[O-])cc3)c21

HCID20269595

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

2 g (7.02 millimols) of tetrachlorophthalimide, 4.36 g (28.08 millimols) of p-nitrothiophenol, 5.82 g (42.12 millimols) of potassium carbonate and 30 ml of tetrahydrofuran are stirred at 25° C. for 14 hours. The mixture is acidified and extracted with tetrahydrofuran/toluene and the extracts are dried and evaporated. The residue is washed with methylene chloride and recrystallised from dioxane/toluene. This yields 3.02 g (57% of theory) of tetrakis-(p-nitrophenylthio)-phthalimide; melting point 297°-301° C.

WORKUP

后处理

extractionextracted with tetrahydrofuran/toluene
customthe extracts are dried
customevaporated
washThe residue is washed with methylene chloride
customrecrystallised from dioxane/toluene

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7ab8869127a04d5fa6892289d1d3f937
来源数据集: uspto-grants-1984_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04459414
来源说明: uspto-grants-1984_07

反应 SMILES

Cl[C:2]1[C:3](Cl)=[C:4](Cl)[C:5](Cl)=[C:6]2[C:11](=[O:12])[NH:10][C:8](=[O:9])[C:7]=12.[N+:16]([C:19]1[CH:24]=[CH:23][C:22]([SH:25])=[CH:21][CH:20]=1)([O-:18])=[O:17].C(=O)([O-])[O-].[K+].[K+]>O1CCCC1>[N+:16]([C:19]1[CH:24]=[CH:23][C:22]([S:25][C:2]2[C:3]([S:25][C:22]3[CH:23]=[CH:24][C:19]([N+:16]([O-:18])=[O:17])=[CH:20][CH:21]=3)=[C:4]([S:25][C:22]3[CH:23]=[CH:24][C:19]([N+:16]([O-:18])=[O:17])=[CH:20][CH:21]=3)[C:5]([S:25][C:22]3[CH:23]=[CH:24][C:19]([N+:16]([O-:18])=[O:17])=[CH:20][CH:21]=3)=[C:6]3[C:11](=[O:12])[NH:10][C:8](=[O:9])[C:7]=23)=[CH:21][CH:20]=1)([O-:18])=[O:17]