反应详情

130 g (1 mole) of 2-methoxysuccinic acid anhydride and 162 g (1 mole) of 3,5-dichloroaniline are heated under reflux for three hours, in 1500 ml of xylene. The resulting water is azeotropically separated off by means of a water separator. The xylene is then distilled off and the crude product is recrystallized from methanol/water. Melting point: 125° to 126° C.; yield: 75% of the theoretical yield.

1. customThe resulting water is azeotropically separated off by means of a water separator
2. distillationThe xylene is then distilled off
3. customthe crude product is recrystallized from methanol/water