Isopropanol → HCID 13337692, compound

HRID 1462991Notes

Reaction equation

HRID 1462991 reaction equation
[C:1]([C:5]1[CH:24]=[CH:23][CH:22]=[CH:21][C:6]=1[C:7]([NH:9][N:10]([CH3:20])[C:11]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[S:12])=[O:8])(OC)=[O:2].C(N)(C)(C)C.[CH:30]([OH:33])([CH3:32])[CH3:31]>>[C:1]([C:5]1[CH:24]=[CH:23][CH:22]=[CH:21][C:6]=1[C:7]([NH:9][N:10]([CH3:20])[C:11]([NH:13][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)=[S:12])=[O:8])([O:33][CH:30]([CH3:32])[CH3:31])=[O:2]

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 6385Tert-ButylamineHCID 13035054HCID 13035054, compound

Product 1

HCID 13337692HCID 13337692, compound

Procedure

To a solution of 5.0 g (0.014 mole) of 1-(2-carbomethoxybenzoyl)-2-methyl-4-phenyl-3-thiosemicarbazide in 75 ml of isopropyl alcohol was added 1.0 g (0.014 mole) of tert-butylamine and the solution was stirred at room temperature for 16-18 hours. Most of the isopropyl alcohol was removed at reduced pressure, and water was added and the resulting precipitate was collected. The title compound thus produced had a melting point of 115°-117°.

Workup

  1. customMost of the isopropyl alcohol was removed at reduced pressure, and water
  2. additionwas added
  3. customthe resulting precipitate was collected

Sources & evidence

ORD record
ord-b852ca5b513243ebb52a9761fb68c93a
Source dataset
uspto-grants-1984_07
Patent number
US04462821

Reaction notes

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