Triethylamine → HCID 15057583, compound

HRID 1463377Notes

Reaction equation

HRID 1463377 reaction equation
[NH2:1][CH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[CH2:4]1.[CH3:15][N:16]([CH2:27][CH2:28][CH2:29][CH2:30]Br)[S:17]([C:20]1[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=1)(=[O:19])=[O:18].C(N(CC)CC)C>CN(C)C=O>[CH3:15][N:16]([CH2:27][CH2:28][CH2:29][CH2:30][NH:1][CH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[CH2:4]1)[S:17]([C:20]1[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=1)(=[O:19])=[O:18]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 15057535HCID 15057535, compoundHCID 15057572HCID 15057572, compound

Product 1

HCID 15057583HCID 15057583, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The compound is prepared from 1 g of 2-aminomethyl-8-methoxytetralin (5.2 mmol), 1.7 g of N-methyl-N-(4-bromobutyl)-4-fluorophenylsulphonamide (5.2 mmol) and 0.73 ml of triethylamine (5.2 mmol) in 20 ml of dimethylformamide analagously to the working directions of Example 47.

Sources & evidence

ORD record
ord-75aa7d50c1e7427cb2dc55dcb0468b8f
Source dataset
uspto-grants-1994_04
Patent number
US05300523

Reaction notes

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