Triethylamine → HCID 67740541, compound

HRID 1463378Notes

Reaction equation

HRID 1463378 reaction equation
[NH2:1][CH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[CH2:4]1.Br[CH2:16][CH2:17][CH2:18][CH2:19][N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]1=[N:26][S:27]([CH3:30])(=[O:29])=[O:28].C(N(CC)CC)C>CN(C)C=O>[CH3:30][S:27]([N:26]=[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][N:20]1[CH2:19][CH2:18][CH2:17][CH2:16][NH:1][CH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[CH2:4]1)(=[O:28])=[O:29]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 15057535HCID 15057535, compoundHCID 54299541HCID 54299541, compound

Product 1

HCID 67740541HCID 67740541, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The compound is prepared from 1.60 g of 2-aminomethyl-8-methoxytetralin (8.4 mmol), 2.28 g of 1-(4-bromobutyl)-2-methylsulfonylimino-1,2-dihydropyridine (7.4 mmol) and 0.85 ml of triethylamine (8.4 mmol) in 32 ml of dimethylformamide analogously to the working directions of Example 51.

Sources & evidence

ORD record
ord-be06122bb0294f459b99de7e24b3b9ce
Source dataset
uspto-grants-1994_04
Patent number
US05300523

Reaction notes

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