Methylamine → HCID 22851212, compound

HRID 1463547Notes

Reaction equation

HRID 1463547 reaction equation
CO[C:3](=[O:14])[C@H:4]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][CH:8]=1)[NH2:5].[CH3:15][NH2:16]>C(O)C>[CH3:15][NH:16][C:3](=[O:14])[C@H:4]([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([NH2:13])=[CH:11][CH:12]=1)[NH2:5]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 206108304-Amino-L-phenylalanine methyl ester

Product 1

HCID 22851212HCID 22851212, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

To a stirred solution of p-aminophenylalanine methyl ester (1.7 g, 8.8 mmol) in ethanol (150 ml) was added methylamine in ethanol (33%/8M) (100 ml). After stirring at room temperature for 24 hours the reaction mixture was reduced under pressure to yield the title compound as a brown solid (1.7 g, 100%)

Sources & evidence

ORD record
ord-125e1dae273a4cdd924102ecc637f885
Source dataset
uspto-grants-1994_04
Patent number
US05300674

Reaction notes

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