Dimethylformamide → HCID 86746383, compound

HRID 1463558Notes

Reaction equation

HRID 1463558 reaction equation
[C:1]([S:9]/[CH:10]=[CH:11]\[C:12]([OH:14])=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CN(C)C=O.C(Cl)(=O)C([Cl:23])=O>ClCCl>[C:1]([S:9]/[CH:10]=[CH:11]\[C:12]([Cl:23])=[O:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 86746382HCID 86746382, compound

Product 1

HCID 86746383HCID 86746383, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a mixture of 7.0 g (0.0336 mol) of cis-3-(benzoylthio)propenoic acid and 0.5 ml of N,N-dimethylformamide in 100 ml of dichloromethane under nitrogen was added 2.93 ml (0.0336 mol) of oxalyl chloride. After 12 h the solvents were removed to give 7.5 g (99% yield) of cis-3-(benzoylthio)propenoyl chloride as a pale yellow solid.

Workup

  1. customAfter 12 h the solvents were removed

Sources & evidence

ORD record
ord-9b1f8b8b4acd4b6b85990aa51f4f1b41
Source dataset
uspto-grants-1994_04
Patent number
US05300672

Reaction notes

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