Acetic Acid → HCID 67877349, compound

HRID 1463934Notes

Reaction equation

HRID 1463934 reaction equation
C([O:4][C@@H:5]1[CH2:12][C@H:11]2[C@H:7]([CH2:8][C:9](=[O:13])[O:10]2)[C@H:6]1[CH2:14][CH:15]1[O:19][CH2:18][CH2:17][O:16]1)(=O)C.C(=O)([O-])[O-].[K+].[K+].C(O)(=O)C>CO>[CH2:17]1[CH2:18][O:19][CH:15]([CH2:14][C@H:6]2[C@H:5]([OH:4])[CH2:12][C@H:11]3[C@@H:7]2[CH2:8][C:9](=[O:13])[O:10]3)[O:16]1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 11430Potassium CarbonateHCID 67877423HCID 67877423, compound

Product 1

HCID 67877349HCID 67877349, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The acetal (55) (4.180 g) was treated with potassium carbonate (1.18 g) in methanol (100 ml) at room temperature for 2 hours with stirring. The reaction mixture was neutralized with addition of acetic acid, followed by the usual work up to give a crude product. The crude product was chromatographed on a column of silica gel to give the alcohol (56).

Workup

  1. customto give a crude product
  2. customThe crude product was chromatographed on a column of silica gel

Sources & evidence

ORD record
ord-574341f5874943c384cda29ece089338
Source dataset
uspto-grants-1994_04
Patent number
US05302617

Reaction notes

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