Methylamine → HCID 23170259, compound

HRID 1464039Notes

Reaction equation

HRID 1464039 reaction equation
I.[C:2]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=[N:12][CH3:13])SC.[CH3:20][NH2:21]>C(O)C>[C:2]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9]([NH:21][CH3:20])=[N:12][CH3:13]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 131718389HCID 131718389, compound

Product 1

HCID 23170259HCID 23170259, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 1-(2-biphenylyl)-2,3-dimethyl-2-thiopseudourea hydriodide (7 g) and a 33% solution of methylamine in ethanol (250 ml) was stirred at ambient temperature for 56 days to give N-(2-biphenylyl)-N',N"-dimethylguanidine (m.p. 101°-102° C.) which was recrystallised from hexane. A sample (2.4 g) was dissolved in methanol (25 ml) and treated with fumaric acid (1.16 g) to give N-(2-biphenylyl)-N',N"-dimethylguanidine fumarate (m.p. 192°-193° C.) which was recrystallised from propan-2-ol.

Sources & evidence

ORD record
ord-a99887bd052245e79593a2c6c3f3332e
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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