4-Methylthio-2-nitrobiphenyl → 2-Amino-4-methylthiobiphenyl

HRID 1464083Notes

Reaction equation

HRID 1464083 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:5]([N+:15]([O-])=O)[CH:4]=1>C(OC(=O)C)C>[NH2:15][C:5]1[CH:4]=[C:3]([S:2][CH3:1])[CH:8]=[CH:7][C:6]=1[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 1

HCID 190892664-Methylthio-2-nitrobiphenyl

Product 1

HCID 190891962-Amino-4-methylthiobiphenyl

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4-Methylthio-2-nitrobiphenyl (15 g) was reduced with hydrated stannous chloride (64 g) in ethylacetate (300 ml) at ambient temperature for 15 hours to give 2-amino-4-methylthiobiphenyl as a yellow oil.

Sources & evidence

ORD record
ord-3094334e8f5e42a299b78fe8a05e823d
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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