Benzoyl isothiocyanate → HCID 15175521, compound

HRID 1464103Notes

Reaction equation

HRID 1464103 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[F:14].[C:15]([N:23]=[C:24]=[S:25])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>ClCCl>[C:15]([NH:23][C:24]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[F:14])=[S:25])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 68284Benzoyl isothiocyanateHCID 15500927HCID 15500927, compound

Product 1

HCID 15175521HCID 15175521, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Reaction of 2-amino-2'-fluorobiphenyl (5 g) with benzoylisothiocyanate (4.4 g) in dichloromethane (120 ml) at ambient temperature for 8 hours gave N-benzoyl-N'-(2'-fluoro-2-biphenylyl)thiourea (m.p. 110°-111° C.).

Sources & evidence

ORD record
ord-e1b839cf6855413ebe9ac5a2c133e48c
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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