Hydrochloric Acid → HCID 19089335, compound

HRID 1464132Notes

Reaction equation

HRID 1464132 reaction equation
[CH2:1]([C:3]1[S:7][C:6]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:5][C:4]=1[CH3:12])[CH3:2].[Cl:13][C:14]1[CH:15]=[C:16]([N:21]=[C:22]=[O:23])[CH:17]=[CH:18][C:19]=1[Cl:20].[OH-].[Na+].Cl>CC(C)=O>[Cl:13][C:14]1[CH:15]=[C:16]([NH:21][C:22]([NH:11][S:8]([C:6]2[S:7][C:3]([CH2:1][CH3:2])=[C:4]([CH3:12])[CH:5]=2)(=[O:9])=[O:10])=[O:23])[CH:17]=[CH:18][C:19]=1[Cl:20]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 76073,4-Dichlorophenyl isocyanateHCID 14798Sodium HydroxideHCID 15669342HCID 15669342, compound

Product 1

HCID 19089335HCID 19089335, compoundYield 27.4%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The procedure of Example 4B was followed with 5-ethyl-4-methyl-2-thiophenesulfonamide (1.5 g, 7.3 mmole), 3,4-dichlorophenyl isocyanate (1.38 g, 7.3 mmole), acetone (7 0 ml), 1H NaOH (7.3 ml), concentrated HCl to give the named product as a white solid (2.17 g, 5 2 mmole).

Sources & evidence

ORD record
ord-38293deeaa6e42d1a3d99b34f5d2889f
Source dataset
uspto-grants-1994_04
Patent number
US05302724

Reaction notes

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