反应详情

22.8 g of 1,3-dihydroxyxanthone (prepared according to Grover, J. Chem. Soc. 1955, 3982) together with 15.2 g of K2CO3 and 21.2 g of 1-bromooctane are refluxed for 15 hours in 250 ml of methyl ethyl ketone. The salt is isolated by filtration from the cooled reaction mixture and the methyl ethyl ketone solution is concentrated by evaporation under vacuum. Recrystallisation of the residue from heptane gives 1-hydroxy-3-octoxyxanthone with a melting point of 98° C.

1. customThe salt is isolated by filtration from the cooled reaction mixture
2. concentrationthe methyl ethyl ketone solution is concentrated by evaporation under vacuum
3. customRecrystallisation of the residue from heptane