反应详情

Compounds of Examples 2 to 7 were obtained by s performing the same reaction as in Example 1 except that the corresponding bromomethyl or chloromethyl derivatives and/or 2-hepten-4-ynylamine derivatives were used instead of the starting compounds, (E)-3-[3--(3-thienyl)-2-propenyloxymethyl]benzyl bromide and/or (E)- N-ethyl-6,6-dimethyl-2-hepten-4-ynylamine hydrochloride, which were used in the above-mentioned reaction. ( When the reaction product was a free base, the hydrochloride producing step in the after-treatment was not included.)

1. customwere used in the above-mentioned reaction