2,2,2-Trifluoroethanol → HCID 131732653, compound

HRID 1464879Notes

Reaction equation

HRID 1464879 reaction equation
[CH2:1]([N:10]=[C:11]=[O:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][N:7]=[C:8]=[O:9].C(Cl)(=O)C1C=CC=C(C(Cl)=O)C=1.[CH2:25]([OH:30])[C:26]([F:29])([F:28])[F:27]>>[N:7]([CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][CH2:1][NH:10][C:11](=[O:12])[O:30][CH2:25][C:26]([F:29])([F:28])[F:27])=[C:8]=[O:9]

Participants

4

Reactant 3

HCID 64092,2,2-TrifluoroethanolHCID 7451Isophthaloyl chlorideHCID 13192Hexamethylene diisocyanate

Product 1

HCID 131732653HCID 131732653, compound

Procedure

684 g of hexamethylene diisocyanate (HDI) were initially introduced at 80° C. in a 1 l round-bottomed flask and 0.002 g of isophthaloyl dichloride was added. 54.4 g of trifluoroethanol were slowly added dropwise and stirring was effected until the NCO value was 43.2% by weight. The mixture was separated by distillation on a thin-film evaporator and 47 g (=47% of theory) of the title compound having an NCO content of 22.7% by weight were obtained.

Workup

  1. customThe mixture was separated by distillation on a thin-film evaporator and 47 g (=47% of theory) of the title compound
  2. customwere obtained

Sources & evidence

ORD record
ord-2ab9f39819014a41a3163df7545c2fee
Source dataset
uspto-grants-2015_04
Patent number
US08999608B2

Reaction notes

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