4-Chlorophenol → HCID 66825962, compound

HRID 1466402Notes

Reaction equation

Cl[C:2]1[N:6]([CH3:7])[N:5]=[C:4]([C:8]([F:11])([F:10])[F:9])[C:3]=1[CH:12]=[O:13].[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=1.C(=O)([O-])[O-:23].[K+].[K+]>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][C:2]2[N:6]([CH3:7])[N:5]=[C:4]([C:8]([F:11])([F:10])[F:9])[C:3]=2[C:12]([OH:13])=[O:23])=[CH:17][CH:16]=1

Participants

Reactant 3

HCID 46844-Chlorophenol

HCID 11430Potassium Carbonate

HCID 14784595-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde

Product 1

HCID 66825962HCID 66825962, compound

Procedure

The title compound was prepared using 5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde and 4-chlorophenol in the manner similar to the method in Production Example 1 above except potassium carbonate was used instead of potassium hydroxide.

Sources & evidence

ORD record: ord-e94e655103f64d3682df1a39db001680
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000024B2

Reaction notes

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