4-Chlorophenol → HCID 66825870, compound

HRID 1466403Notes

Reaction equation

Cl[C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH:8]([F:10])[F:9])[C:3]=1[CH:11]=[O:12].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=1.C(=O)([O-])[O-:22].[K+].[K+]>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][C:2]2[N:6]([CH3:7])[N:5]=[C:4]([CH:8]([F:10])[F:9])[C:3]=2[C:11]([OH:12])=[O:22])=[CH:16][CH:15]=1

Participants

Reactant 3

HCID 46844-Chlorophenol

HCID 11430Potassium Carbonate

HCID 197546925-Chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde

Product 1

HCID 66825870HCID 66825870, compound

Procedure

The title compound was prepared using 5-chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde and 4-chlorophenol in the manner similar to the method in Production Example 1 above except potassium carbonate was used instead of potassium hydroxide.

Sources & evidence

ORD record: ord-96647ee772394628adcbfd379cb05d46
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000024B2

Reaction notes

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