HCID 89499916, compound → HCID 43808402, compound

HRID 1467806Notes

Reaction equation

HRID 1467806 reaction equation
[CH:1]1[C:10]2[C:5](=[C:6]([N:11]3[CH2:16][CH2:15][CH2:14][CH2:13][C:12]3=[O:17])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1>CCO.O=[Pt]=O>[CH2:1]1[C:10]2[C:5](=[C:6]([N:11]3[CH2:16][CH2:15][CH2:14][CH2:13][C:12]3=[O:17])[CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][NH:2]1

Participants

4

Reactant 1

HCID 89499916HCID 89499916, compound

Product 1

HCID 43808402HCID 43808402, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 702EthanolSolvent

Procedure

33A was hydrogenated at 55 psi in EtOH (20 mL) in the presence of PtO2 (30 mg). After 24 h, the reaction was filtered through Celite® and concentrated to afford 0.4 g of dark oil as desired product. MS (ESI) m/z: 231.3 (M+H)+.

Workup

  1. filtrationthe reaction was filtered through Celite®
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-35207ff0494943a885a84667cb689404
Source dataset
uspto-grants-2015_04
Patent number
US09000172B2

Reaction notes

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