2-Bromoethyl methyl ether → HCID 66859217, compound

HRID 1470020Notes

Reaction equation

HRID 1470020 reaction equation
[NH2:1][C:2]1[S:3][C:4]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[CH:5][N:6]=1.[CH3:12][O:13][CH2:14][CH2:15][Br:16]>>[BrH:16].[NH:1]=[C:2]1[N:6]([CH2:15][CH2:14][O:13][CH3:12])[CH:5]=[C:4]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[S:3]1

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 3146282-Amino-thiazole-5-carboxylic acid ethyl ester

Product 1

HCID 66859217HCID 66859217, compound

Procedure

A mixture of commercially available ethyl 2-aminothiazole-5-carboxylate (ABCR) and 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound. MS (ESI+) m/z 231 (M+H)+.

Sources & evidence

ORD record
ord-a46ef10e2235455e8f3acd560f8e5dc3
Source dataset
uspto-grants-2015_04
Patent number
US09006275B2

Reaction notes

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