Methanesulfonic Acid → 2-Isocyanatoethyl methacrylate

HRID 1470772Notes

Reaction equation

HRID 1470772 reaction equation
N1([C:6]([NH:8][CH2:9][CH2:10][O:11][C:12](=[O:16])[C:13]([CH3:15])=[CH2:14])=[O:7])C=CN=C1.CS(O)(=O)=O.ClCl>>[N:8]([CH2:9][CH2:10][O:11][C:12](=[O:16])[C:13]([CH3:15])=[CH2:14])=[C:6]=[O:7]

Participants

4

Reactant 3

HCID 6395Methanesulfonic AcidHCID 24526ChlorineHCID 67424696HCID 67424696, compound2×

Product 1

HCID 354092-Isocyanatoethyl methacrylate

Procedure

This substance was synthesized according to the procedure described in Example 4, second step. 2-Methyl-acrylic acid 2-[(imidazole-1-carbonyl)-amino]-ethyl ester was used from Example 5. Dry methane sulfonic acid was used to protononate and decompose the 2-Methyl-acrylic acid 2-[(imidazole-1-carbonyl)-amino]-ethyl ester. 39.1 g MOI were received after fractionation (62.1% of theory); purity of 97.5%; residual chlorine: not detectable.

Workup

  1. customThis substance was synthesized

Sources & evidence

ORD record
ord-3d45f593359641668c730dcff8f4a4df
Source dataset
uspto-grants-2015_04
Patent number
US09006480B2

Reaction notes

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