反应详情

A solution of cyclohexanone (98.1 g, 1 mol), allyl alcohol (127.8 g, 2.2 mol), dimethoxypropane (114.6 g, 1.1 mol), and PTSA.H2O (0.1 g, 0.5 mmol) in toluene (0.51) was heated at reflux in a flask equipped with a microdistillation column (30×2.5 cm, filled with Raschig rings). After collecting the fractions distilling at 25-60° C. and 60-110° C., the residue (120 g) was distilled using a 10 cm-Vigreux-column (0.07-0.06 mbar, head temperature: 57° C.) giving 2-allylcyclohexanone (99.1 g, 72%).

1. temperatureat reflux in a flask
2. customequipped with a microdistillation column (30×2.5 cm, filled with Raschig rings)
3. customAfter collecting the fractions
4. distillationdistilling at 25-60° C. and 60-110° C.
5. distillationthe residue (120 g) was distilled
6. customa 10 cm-Vigreux-column (0.07-0.06 mbar, head temperature: 57° C.)