Dichloromethane → Ethyl 4-(3-cyano-4-fluorobenzyl)piperazine-1-carboxylate
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]2)[cH:20][cH:21][c:22]1[F:23].[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[Cl:31][C:32]([O:33][CH2:34][CH3:35])=[O:36].[Cl:37][CH2:38][Cl:39].[F:40][C:41]([F:42])([F:43])[C:44]([OH:45])=[O:46]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:11][CH2:12]2)[cH:20][cH:21][c:22]1[F:23]Participants
6
Sources & evidence
- ORD record
- ord-a909cc7de250470d86832e90930e7044
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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