Ethanol → 6-(2-Chlorophenyl)-5-(4-chlorophenyl)-2-[(3,4-difluorobenzyl)oxy]nicotinamide
Reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][O:52][CH2:53]1.[CH3:45][CH2:46][OH:47].[Cl:1][c:2]1[c:3](-[c:8]2[n:9][c:10]([O:23][CH2:24][c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[c:11]([C:12]#[N:13])[cH:14][c:15]2-[c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[cH:4][cH:5][cH:6][cH:7]1.[F:33][C:34]([F:35])([F:37])[C:38](=[O:36])[OH:39].[K+:41].[OH-:40].[OH2:44].[OH:42][OH:43]>>[Cl:1][c:2]1[c:3](-[c:8]2[n:9][c:10]([O:23][CH2:24][c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[c:11]([C:12]([NH2:13])=[O:36])[cH:14][c:15]2-[c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[cH:4][cH:5][cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-14ffac98da994dddb28c6f8c3c05fe5b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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