Dimethylformamide → HCID 178526296, compound

HRID 1472691Notes

Reaction equation

HRID 1472691 reaction equation
O[C:2]1[N:3]=[N+:4]([O-:13])[C:5]2[CH:11]=[C:10]([OH:12])[CH:9]=[CH:8][C:6]=2[N:7]=1.CN(C=O)C.O=P(Cl)(Cl)[Cl:21]>>[Cl:21][C:2]1[N:3]=[N+:4]([O-:13])[C:5]2[CH:11]=[C:10]([OH:12])[CH:9]=[CH:8][C:6]=2[N:7]=1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 178526298HCID 178526298, compound

Product 1

HCID 178526296HCID 178526296, compound

Procedure

1 g of 3,7-dihydroxybenzo[e][1,2,4]triazine 1-oxide was suspended in POCl3 (20 mL) and DMF (0.1 mL) and stirred at 100° C. for 2 h. The solution was cooled, poured into ice/water (200 mL), stirred for 30 min, filtered, washed with water (3×10 mL) and dried.

Workup

  1. temperatureThe solution was cooled
  2. filtrationfiltered
  3. washwashed with water (3×10 mL)
  4. customdried

Sources & evidence

ORD record
ord-60d5ecd9bdac4837923d0e4d6563b9b5
Source dataset
uspto-grants-2015_04
Patent number
US09012646B2

Reaction notes

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