Tetrahydrofuran → N-(2,4-dimethoxybenzyl)-5-iodo-N-(thiazol-2-yl)pyridine-2-sulfonamide
Reaction equation
[CH3:18][Si:19]([CH3:20])([CH3:21])[N-:22][Si:23]([CH3:24])([CH3:25])[CH3:26].[CH3:1][O:2][c:3]1[c:4]([CH2:5][NH:6][c:7]2[s:8][cH:9][cH:10][n:11]2)[cH:12][cH:13][c:14]([O:16][CH3:17])[cH:15]1.[I:28][c:29]1[cH:30][cH:31][c:32]([S:35](=[O:36])(=[O:37])[Cl:38])[n:33][cH:34]1.[Li+:27].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][N:6]([c:7]2[s:8][cH:9][cH:10][n:11]2)[S:35]([c:32]2[cH:31][cH:30][c:29]([I:28])[cH:34][n:33]2)(=[O:36])=[O:37])[cH:12][cH:13][c:14]([O:16][CH3:17])[cH:15]1Participants
6
Sources & evidence
- ORD record
- ord-a4d2bad36f864eaaa18159f1e28f7f59
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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