反应详情

温度

5 °C

Triphosgene (29.8 g, 0.1 mol) and 50 mL of carbon tetrachloride were added into 250 mL of flask in sequence, the mixture was cooled to 5° C. below by ice bath, then the solution of phenylmethanol (10.8 g, 0.1 mol) and 20 mL of carbon tetrachloride were dropwise to the reaction solution followed by stirring for 5 hours at room temperature after removing ice bath. The reaction was monitored by thin-layer chromatography (TLC). Upon completion the mixture was added ethyl acetate, the organic phase was washed by water and then evaporated under reduced pressure to obtain 16.3 g of colorless of oil with yield of 95.6%.

1. customafter removing ice bath
2. additionUpon completion the mixture was added ethyl acetate
3. washthe organic phase was washed by water
4. customevaporated under reduced pressure
5. customto obtain 16.3 g of colorless of oil with yield of 95.6%