Diethylcarbamoyl chloride → HCID 86654178, compound

HRID 1476002Notes

Reaction equation

[OH:1][NH:2][C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6].[CH2:10]([N:12]([CH2:16][CH3:17])[C:13](Cl)=[O:14])[CH3:11]>>[CH2:10]([N:12]([CH2:16][CH3:17])[C:13](=[O:14])[O:1][NH:2][C:3]([O:4][C:5]([CH3:8])([CH3:7])[CH3:6])=[O:9])[CH3:11]

Participants

Reactant 2

HCID 6916Diethylcarbamoyl chloride

HCID 97534tert-butyl N-hydroxycarbamate

Product 1

HCID 86654178HCID 86654178, compound

Procedure

[(tert-Butoxy)carbonyl]amino N,N-diethylcarbamate is prepared from tert-butyl N-hydroxycarbamate and diethyl carbamoyl chloride according to Scheme 1. (0.67 g, 39%), 1H NMR (500 MHz, CHLOROFORM-d) δ ppm 7.84 (1H, br. s.), 3.33 (4H, q, 7.1 Hz), 1.48 (9H, s), 1.11-1.28 (6H, m).

Sources & evidence

ORD record: ord-25009dddb78b43dbb1b3d3a0e1f7d94a
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09018411B2

Reaction notes

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