反应详情

Example 6 is repeated with 66 g (0.5 mol) of phosphinic acid, 114.5 g (0.5 mol) of hexadecene, 23 mg of tris(dibenzylideneacetone)dipalladium and 32 mg of 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene in 500 g of tetrahydrofuran, passed through a column charged with Deloxan® THP II for purification and freed of solvent in a rotary evaporator. The residue is admixed with 500 g of completely ion-free water and stirred, and then filtered and the residue is washed with cold water and acetone to obtain 127 g (81% of theory) of hexadecylphosphonous acid.

1. customfreed of solvent in a rotary evaporator
2. filtrationfiltered
3. washthe residue is washed with cold water and acetone