Hydroxylamine → HCID 43248107, compound

HRID 1476672Notes

Reaction equation

HRID 1476672 reaction equation
[CH2:1]([O:4][CH2:5][C:6]#[N:7])[CH2:2][CH3:3].[NH2:8][OH:9]>C(Cl)Cl>[OH:9]/[N:8]=[C:6](\[NH2:7])/[CH2:5][O:4][CH2:1][CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 787HydroxylamineHCID 1898092366502-25-8

Product 1

HCID 43248107HCID 43248107, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of propoxyacetonitrile (3.03 g) and hydroxylamine (2.01 g, 50 wt % in water) is stirred for 2 h at 100° C. At RT DCM is added, the organic phase is separated, dried over sodium sulfate and concentrated under reduced pressure to give the title compound as an oil.

Workup

  1. customthe organic phase is separated
  2. dry with materialdried over sodium sulfate
  3. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-1489afd5ce5c4c1e95fdd821af9fbff7
Source dataset
uspto-grants-2015_04
Patent number
US09018175B2

Reaction notes

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