HRID1478942

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

HCID11776

Triphenylphosphine

C18H15P

结构：C[Si](C)(C)O[Si](CCCI)(O[Si](C)(C)C)O[Si](C)(C)C

HCID22325693

未命名化合物

PRODUCTS

生成物

结构：C[Si](C)(C)O[Si](CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)(O[Si](C)(C)C)O[Si](C)(C)C.[I-]

HCID87426320

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

1.0 g of 3-iodopropyltris(trimethylsiloxy)silane (28) described in Step 6.1, 1.7 g of triphenylphosphine and 0.69 g of sodium carbonate are added to 50 ml of tetrahydrofurane. The reaction mixture is stirred for 2 days at reflux. The solvent is evaporated and the residue purified by column chromatography on silica gel to give the desired phosphonium salt (37); ESI-MS: M+599.58.

WORKUP

后处理

temperatureat reflux
customThe solvent is evaporated
customthe residue purified by column chromatography on silica gel

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b626b74765b84d35a41aaeb7b64376e0
来源数据集: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09403987B2
来源说明: uspto-grants-2016_08

反应 SMILES

[I:1][CH2:2][CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8].[C:21]1([P:27]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.C(=O)([O-])[O-].[Na+].[Na+]>O1CCCC1>[I-:1].[C:34]1([P+:27]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:2][CH2:3][CH2:4][Si:5]([O:16][Si:17]([CH3:20])([CH3:19])[CH3:18])([O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[O:6][Si:7]([CH3:10])([CH3:9])[CH3:8])[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1