Nitric Acid → HCID 5324398, compound

HRID 1479698Notes

Reaction equation

HRID 1479698 reaction equation
S(=O)(=O)(O)O.[N+:6]([O-:9])(O)=[O:7].[CH:10]1[C:15]([C:16]2[C:25](=[O:26])[C:24]3[CH:23]=[CH:22][C:21]([OH:27])=[CH:20][C:19]=3[O:18][CH:17]=2)=[CH:14][CH:13]=[C:12]([OH:28])[CH:11]=1.O>C(O)C>[OH:27][C:21]1[CH:20]=[C:19]2[C:24]([C:25](=[O:26])[C:16]([C:15]3[CH:10]=[CH:11][C:12]([OH:28])=[C:13]([N+:6]([O-:9])=[O:7])[CH:14]=3)=[CH:17][O:18]2)=[CH:23][CH:22]=1

Participants

6

Reactant 4

HCID 944Nitric AcidHCID 962WaterHCID 1118Sulfuric AcidHCID 5281708Daidzein

Product 1

HCID 5324398HCID 5324398, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

20 ml of a mixture of concentrated sulfuric acid and nitric acid (3:1) are added dropwise to a solution of 1 g of daidzein in 200 ml of dry ethanol at room temperature while stirring vigorously. The mixture is stirred for another 2 hours, and 400 ml of water are then added. The compound precipitates, is filtered off with suction and washed with water until neutral. The yellow product is recrystallized from alcohol.

Workup

  1. stirringThe mixture is stirred for another 2 hours
  2. customThe compound precipitates
  3. filtrationis filtered off with suction
  4. washwashed with water until neutral
  5. customThe yellow product is recrystallized from alcohol

Sources & evidence

ORD record
ord-0d98c916f9634535a4978387a63ea6e0
Source dataset
uspto-grants-2016_08
Patent number
US09409859B2

Reaction notes

Loading…