HRID1480450

反应详情

EQUATION

反应方程式

HRID 1480450 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

2

PROCEDURE

实验过程

A solution of (E)-N-(1-(3-(3,5-dichlorophenyl)acryloyl)piperidin-4-yl)-4-(1H-1,2,3-triazol-4-yl)butanamide (Example 38) (70 mg, 0.160 mmol) in EtOH (6 ml) was allowed to pass through the H cube fitted with a 10% Pt/C catalytic cartridge for 3 hours. The reaction mixture was concentrated under reduced pressure to afford the title product;

WORKUP

后处理

  1. concentrationThe reaction mixture was concentrated under reduced pressure