Hydrochloric Acid → HCID 90218956, compound

HRID 1480464Notes

Reaction equation

HRID 1480464 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:23]=[C:24]([Cl:26])[CH:25]=1)[CH2:5][O:6][C:7]([NH:9][CH:10]1[CH2:15][CH2:14][N:13](C(OC(C)(C)C)=O)[CH2:12][CH2:11]1)=[O:8].Cl>O1CCOCC1>[NH:13]1[CH2:14][CH2:15][CH:10]([NH:9][C:7](=[O:8])[O:6][CH2:5][C:4]2[CH:3]=[C:2]([Cl:1])[CH:25]=[C:24]([Cl:26])[CH:23]=2)[CH2:11][CH2:12]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86722689HCID 86722689, compound

Product 1

HCID 90218956HCID 90218956, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A reaction mixture comprising tert-butyl 4-((((3,5-dichlorobenzyl)oxy)carbonyl)amino)piperidine-1-carboxylate (2.01 g, 4.98 mmol) and 4M HCl in dioxane (1.246 ml, 4.98 mmol) in dioxane (16.61 ml) was stirred at room temperature for 1 hour. The resulting mixture was concentrated under reduced pressure. No further purification under taken and the material was dried and taken on to the next step.

Workup

  1. concentrationThe resulting mixture was concentrated under reduced pressure
  2. customNo further purification
  3. customthe material was dried

Sources & evidence

ORD record
ord-3e7c472a67d447c1a38f162c6b5b31a9
Source dataset
uspto-grants-2016_08
Patent number
US09409895B2

Reaction notes

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