反应详情

2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine hydrochloride was prepared from 2-(5-tert-butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-6-(2-chloro-phenyl)-4-methoxy-3H-imidazo[4,5-c]pyridine prepared as described in Example 25) according to the procedure described in Example 2, STEP C substituting 6M HCl in IPA with 2M HCl in Et2O. 1H-NMR (CD3OD) δ: 7.69-7.65 (m, 1H), 7.53-7.60 (m, 2H), 7.42-7.49 (m, 2H), 4.40 (s, 3H), 4.10 (s, 3H), 1.47 (s, 9H). Mass Spectrum (LCMS, ESI pos.) Calculated for C21H21N5OCl2: 430.1 (M+H). Measured: 430.2.

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