Tetrahydrofuran → 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-[(5-isopropyl-2,5-diazabicyclo[2.2.1]hept-2-yl)sulfonyl]-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one
Reaction equation
[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH:11]([N:12]([CH:13]([CH3:14])[CH3:15])[CH2:16][CH3:17])([CH3:18])[CH3:19].[CH:1]([CH3:2])([CH3:3])[N:4]1[CH:5]2[CH2:6][NH:7][CH:8]([CH2:9]1)[CH2:10]2.[Cl:20][c:21]1[c:22](-[c:27]2[c:28]3[c:33]([cH:34][c:35]([S:37](=[O:38])(=[O:39])[Cl:40])[cH:36]2)[N:32]([c:41]2[c:42]([Cl:48])[cH:43][cH:44][cH:45][c:46]2[Cl:47])[C:31](=[O:49])[N:30]([CH2:50][c:51]2[cH:52][cH:53][c:54]([O:57][CH3:58])[cH:55][cH:56]2)[CH2:29]3)[cH:23][cH:24][cH:25][cH:26]1>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH:5]2[CH2:6][N:7]([S:37]([c:35]3[cH:34][c:33]4[c:28]([c:27](-[c:22]5[c:21]([Cl:20])[cH:26][cH:25][cH:24][cH:23]5)[cH:36]3)[CH2:29][N:30]([CH2:50][c:51]3[cH:52][cH:53][c:54]([O:57][CH3:58])[cH:55][cH:56]3)[C:31](=[O:49])[N:32]4[c:41]3[c:42]([Cl:48])[cH:43][cH:44][cH:45][c:46]3[Cl:47])(=[O:38])=[O:39])[CH:8]([CH2:9]1)[CH2:10]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4ac88c34f0224ce799e07709d3e8c40a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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