Tetrahydrofuran → 4-[4-(2,2-Dimethyl-3-pyrrolidin-1-ylpropoxy)phenyl]tetrahydro-pyran-4-carbonitrile
Reaction equation
[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:16][C:17]([CH2:18][OH:19])([CH2:20][N:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1)[CH3:26].[O:46]=[C:47]([O:48][CH:49]([CH3:50])[CH3:51])[N:52]=[N:53][C:54]([O:55][CH:56]([CH3:57])[CH3:58])=[O:59].[OH:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:6][cH:7]1)[CH2:18][C:17]([CH3:16])([CH2:20][N:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1)[CH3:26]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1475ffde842e42d18936cd58fec5573d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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