Chlorosuccinimide → HCID 131736715, compound

HRID 1482902Notes

Reaction equation

HRID 1482902 reaction equation
[Cl:1]N1C(=O)CCC1=O.[C:9]1([NH:15][N:16]=[CH:17][C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>CN(C=O)C>[Cl:1][N:15]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[N:16]=[CH:17][C:18]1[CH:19]=[CH:20][N:21]=[CH:22][CH:23]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 5189360HCID 5189360, compound

Product 1

HCID 131736715HCID 131736715, compoundYield 52.4%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

N-Chlorosuccinimide (2.11 g, 16 mmol) was added portionwise to a solution of compound 1 (2.97 g, 15 mmol) in DMF (15 mL). The reaction mixture was stirred for 10 min at room temperature. The resulting precipitates were collected and washed with petroleum ether to afford 1.82 g (52%) of 2 as a solid.

Workup

  1. customThe resulting precipitates
  2. customwere collected
  3. washwashed with petroleum ether

Sources & evidence

ORD record
ord-1a5e8d447f524071a60d2d04e9ab6da8
Source dataset
uspto-grants-2016_08
Patent number
US09416123B2

Reaction notes

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